I am broadly interested in the mechanisms of allostery in biomolecules and their implications for protein function and regulation. My research employs Molecular Dynamics simulations and network-based methods to investigate how external factors—such as mutations and environmental changes like temperature variations—impact allostery and protein function. The objective of my research is to deepen our understanding of these processes, particularly in relation to identifying new therapeutic targets. By studying the cross-correlated interactions between different physicochemical factors and their influences on the energy landscape of macromolecular systems, my work aims to provide a physical rationale for the alterations and signaling pathways that drive allosteric behavior. Ultimately my research seeks to enhance our methods for enzyme control and modulation.
